R&D

 

Our 22,000 sq. ft R&D facility in Bangalore is designed to handle up to BSL-2 level organisms and is certified to meet ISO 9001:2008 standards.

The facility incorporates the latest bioprocess engineering and analytical equipment to support development in microbial & mammalian expression systems.



research and development
 

Upstream Development

  • Cell bank storage (-80°C & liquid nitrogen)
  • Micro-bioreactor based media optimization
  • Microbial fermentation from shake flasks up to 20 L scale
  • Mammalian fermentation up to 10L scale
  • Parallel Bioreactors for DoE modules
  • Spent media analysis (Biochemical + Amino acid analyser)
 
  • Upstream Development
  • Upstream Development
 

Downstream Development

  • Low & high pressure chromatography systems up to 1LPM capacity with columns up to 100mm (low pressure) and 150mm (DAC)
  • Depth & cross flow filtration process development- up to 0.5 sq.m area
  • Refolding capacity up to 300L
  • High pressure homogenizers for cell lysis
  • Dedicated conjugation area
 
  • Downstream Development
  • Downstream Development
  • Downstream Development
 

Formulation Development

  • Capacity for manual filling - vials, prefilled syringes & cartridges; Lyophilizer for lyophilized formulation development
 
  • Formulation Development
  • Formulation Development

Analytical Development

  • Equipped with HPLCs & UPLCs for SEC, CEX, RP-HPLC based method development
  • Clone analysis using tools such as gel electrophoresis, western blot, biolayer interferometry, RTPCR
  • Thermal stability analysis using Differential scanning colorimetry
 
  • Analytical Development
  • Analytical Development
 
research and development